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Wall Street ended Tuesday lower overall as investors awaited both key central bank decisions and next week’s Brexit referendum in Great Britain.

The S&P 500 ended the day down 0.2% at 2,075.32. The Dow was off 0.33% at 17,674.82 and Nasdaq closed down 0.10% at 4,843.55.

Related: EARNINGS CALENDAR WEEK OF: JUNE 13, 2016

Here are the biggest losers and gainers on the day.

Synchrony Financial (NYSE:SYFC)

After disclosing higher than expected charge off rates, Synchrony ended the day off more than 13%, the highest one-day decline in company history.

Santander Consumer USA Holdings (NYSE:SCB)

Santander’s 8.12% fall from grace came courtesy of bearish performance in 4 key technical indicators.

Dynegy Inc. (NYSE:DYNB)

After dropping as much as 11%, Dynegy closed down 7.11% on a downgrade from Citigroup from “buy” to “neutral.” The company has reported losses for 3 straight quarters.

SLM Corporation (NASDAQ:SLMC)

Student loan debt above $1.3 trillion put SLM on InvestorPlace’s short list of stocks to short, along with Navient NAVI and Nelnet NNI. SLM fell nearly 7% Tuesday on volume of more than 5 million shares.

Platform Specialty Products Corp. (NYSE:PAHB)

Despite a share price drop of 6.62% Tuesday, Platform Specialty Products’ stock has shown a 30-day trend of 2.07%, putting it around the peer median. In addition, the company made Insider Monkey’s list of 5 Stocks Backers of CIRCA like.

Perigo Company plc (NASDAQ:PRGOC)

A takeover rumor caused a spike in Perigo stock Tuesday resulting in shares closing at $108.13, up more than 9% on the day. The reported acquiring company has not been named.

Twitter Inc. (NYSE:TWTRC)

Following Microsoft’s planned takeover of LinkedIn, Twitter rose 5.57% Tuesday on speculation that it might be a likely next target. Leading takeover contenders include Amazon (NASDAQ:AMZNC), Alphabet (NASDAQ:GOOGB) and Verizon (NYSE:VZC).

Laredo Petroleum Inc. (NYSE:LPIB)

Thanks to an upgrade from “sector perform” to “outperform” by Iberia, Laredo stock spiked 4.8% Tuesday, ending the day at $11.57.

Ionis Pharmacutis (NASDAQ:IONSB)

The headline on The Point Review reads: Ionis Pharmaceuticals Has Propensity to Increase 171%. That was enough to boost IONS share prices 4.10% to $22.35 Tuesday.

Related: Why Microsoft Wants To Buy LinkedIn

Zynga Inc. (NASDAQ:ZNGAC)

As with Twitter, Zynga’s 3.54% bump Tuesday was also likely the result of “me too” talk regarding the company’s potential to be acquired.



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